In response to the COVID-19 epidemic, in order to enhance the protection of HIV-infected people against COVID-19, medical staff from the Department of Disease Management of Keelung City Health Bureau and the Department of Infectious Diseases of Keelung Chang Gung Memorial Hospital went to the detention center to administer the COVID-19 vaccine to 4 HIV-infected patients. Prevent AIDS patients from getting worse after infection. And promote the importance of wearing a mask and washing hands frequently.